|
|
(2E,6E)-farnesyl_diphosphate <=> amorpha-4,11-diene + diphosphate
|
4.2.3.24
amorpha-4,11-diene synthase
|
–
|
BMK
|
|
BRENDA:
BR48696
KEGG:
R07630
MetaCyc:
RXN-8046
|
|
|
|
amorpha-4,11-diene + 3 O2 + 3 reduced_flavodoxin <=> artemisinate + 3 flavin + 4 H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BR50104
KEGG:
R10026
|
|
|
|
amorpha-4,11-diene + O2 + reduced_flavodoxin <=> artemisinic_alcohol + flavin + H2O
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
B
|
|
BRENDA:
BR50356
KEGG:
R10023
|
|
|
|
amorpha-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinate + oxidized_[NADPH-hemoprotein_reductase] + H2O + H+
|
1.14.14.114
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
MetaCyc:
RXN-13432
|
|
|
|
amorpha-4,11-diene + O2 + reduced_[NADPH-hemoprotein_reductase] <=> artemisinic_alcohol + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
not assigned
|
–
|
M
|
|
MetaCyc:
RXN-8050
|
|
|
|
geranyl_diphosphate + H2O <=> amorpha-4,11-diene + diphosphate
|
4.2.3.24
amorpha-4,11-diene synthase
|
–
|
|
|
BRENDA:
BS381948
|
|
|
|
amorpha-4,11-diene + O2 + NADPH + H+ <=> artemisinic_alcohol + NADP+ + H2O
|
1.14.13.158
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BS442274
|
|
|
|
amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+ <=> artemisinate + 3 NADP+ + 4 H2O
|
1.14.13.158
amorpha-4,11-diene 12-monooxygenase
|
–
|
|
|
BRENDA:
BS442272
|
|